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Dr. Carl D. Meinhart, President and CEO

Dr. Carl D. Meinhart is the President and CEO of Numerical Design Inc. He leads the NDI technical team, and has 14 years of COMSOL experience of solving problems ranging from fundamental microfluidics research to analysis of commercial products and is a COMSOL Certified Consultant. Dr. Meinhart is a Professor of Mechanical Engineering at the University of California, Santa Barbara. He holds seven patents, 65+ publications, and is a Fellow of the American Physics Society.

In 1996, Dr. Meinhart joined the faculty in the Dept. of Mechanical Engineering at UCSB. He was promoted to full professor in 2007. He is well known for his work in co-developing micron-resolution Particle Image Velocimetry. This technique is widely used in the research community for measuring detailed fluid motion in microfluidic devices. In collaboration with Prof. Martin Moskovits group in Chemistry at UCSB, Dr. Meinhart co-invented a Free-surface microfluidics / SERS technique for detection of certain gas-phase molecules with ultrahigh sensitivity and specificity. The technique is applicable to the detection of vapors emanating from explosives and narcotics, among others.

Complete CV

Selected Publications

Dr. Brian D. Piorek, CTO

Dr. Brian D. Piorek serves as CTO of Numerical Design Inc. where he works with a variety of clients ranging from small to large companies. His primary duties involve the development of strategic relationships with new and existing companies, management and execution of various technical projects, and the development and implementation of intellectual property targeted towards specific projects.

Brian holds a B.S. degree in Chemical Engineering and a Ph.D. degree in Mechanical Engineering from the University of California Santa Barbara. Brian’s research has focused on fluid transport phenomena and the development of microfluidic/nanoscale systems and chemical detection mechanisms. He has 12 years experience developing multiphase fluid systems and reactors based on chemical engineering principles and 9 years experience working specifically with MEMS and microfluidics. Brian holds 5 issued patents and 9 peer-reviewed publications.

Complete CV

Selected Publications

Selected Publications by Carl Meinhart

Marshall, L.A., Rogacs, A., Meinhart, C.D., and Santiago, J.G. An injection molded microchip for nucleic acid purification from 25 microliter samples using isotachophoresis. J. Chromatography A, 2014, http://dx.doi.org/10.1016/j.chroma.2014.01.036.

Piorek, B. D., Andreou, C. Moskovits, M., Meinhart, C.D. Discrete free-surface millifluidics for rapid capture and analysis of airborne molecules using surface-enhanced Raman spectroscopy. Anal. Chem. 2014, 86,1061-1066. dx.doi.org/10.1021/ac402628t.

Andreou, C., Hoonejani, M.R., Barmi, M.R., Moskovits, M., Meinhart, C.D. Rapid detection of drugs of abuse in saliva using surface enhanced Raman spectroscopy and microfluidics. ACS Nano, Vol. 7, No. 8, pp. 7157-7164, 2013.

Piorek, B., Lee, S-J., Moskovits, M. and Meinhart, C.D. 2012. Free-surface microfluidics / SERS for real-time vapor detection of explosives, Anal. Chem. 84, 9700-9705. Srivastava, N., Ding, C., Judson, A., MacDonald, N., and Meinhart, C.D. 2010. A unified scaling model for flow through a lattice of microfabricated posts, Lab on a Chip, 10, 1148-1152.

Hsiang-Wei Lu, Frederic Bottausci, Jesse D Fowler, Andrea L Bertozzi, Carl Meinhart, Chang-Jin Cj Kim. 2008. A study of EWOD-driven droplets by PIV investigation. Lab on a Chip, Vol. 8 (3), pp. 456-61.

Pennathur, S., Meinhart, C.D., and Soh, T.H. 2008. How to Exploit the Features of Microfluidics Technology. Lab on a Chip Vol. 8, 20-22.

Piorek, B.D, Lee, S.-J., Santiago, J.G., Moskovits, M., Banerjee, S. & Meinhart, C. D. 2007 Free-surface microfluidic control of surface enhanced Raman spectroscopy for the optimized detection of airborne molecules Proc. Nat. Acad. Sci. 104, 18898-18901.

Selected Publications by Brian Piorek

Brian D. Piorek, Chrysafis Andreou, Martin Moskovits and Carl D. Meinhart Discrete Free-Surface Millifluidics for Rapid Capture and Analysis of Airborne Molecules Using Surface-Enhanced Raman Spectroscopy Anal. Chem (2014) 86 2 1061-1066. DOI: 10.1021/ac402628t.

Brian D. Piorek, Seung Joon Lee, Martin Moskovits and Carl D. Meinhart Free-Surface Microfluidics/Surface-Enhanced Raman Spectroscopy for Real-Time Trace Vapor Detection of Explosives Anal. Chem (2012) 84 22 9700-9705. DOI: 10.1021/ac302497y.

Changsong Ding, Gaurav Soni, Payam Bozorgi, Brian D. Piorek, Carl D. Meinhart and Noel C. MacDonald A Flat Heat Pipe Architecture Based on Nanostructured Titania J. MEMS (2010) 99 1-7. DOI: 10.1109/JMEMS.2010.2051019.

Seung Joon Lee, Brian D. Piorek, Carl D. Meinhart and Martin Moskovits Photoreduction at a Distance: Facile, Nonlocal Photoreduction of Ag Ions in Solution by Plasmon-Mediated Photoemitted Electrons Nano Lett. (2010) 10 4 1329-1334.

Brian D. Piorek, Seung Joon Lee, Juan G. Santiago, Martin Moskovits, Sanjoy Banerjee and Carl D. Meinhart Free-surface microfluidic control of surface-enhanced Raman spectroscopy for the optimized detection of airborne molecules Proc. Natl. Acad. Sci. USA (2007) 104 48 18898-18901. DOI: 10.1073/pnas.0708596104.

Patrick E. Freudenthal, Matt Pommer, Carl D. Meinhart and Brian D. Piorek Quantum nanospheres for sub-micron particle image velocimetry Exp. Fluids (2007) 43 525-533. DOI: 10.1007/s00348-007-0316-0.

Brian Piorek, Adam Mechler, Ratnesh Lal, Patrick Freudenthal, Carl Meinhart and Sanjoy Banerjee Nanoscale resolution microchannel flow velocimetry by atomic force microscopy Appl. Phys. Lett. (2006) 89 153123-153125. DOI: 10.1063/1.2358966.

Yi Xiao, Brian D. Piorek, Kevin W. Plaxco and Alan J. Heeger A Reagentless Signal-On Architecture for Electronic, Aptamer-Based Sensors via Target-Induced Strand Displacement J. Am. Chem. Soc. (2005) 127 51 17990-17991. DOI: 10.1021/ja056555h.

Adam Mechler, Brian Piorek, Ratnesh Lal and Sanjoy Banerjee Nanoscale velocity-drag force relationship in thin liquid layers measured by atomic force microscopy Appl. Phys. Lett. (2004) 85 17 3881-3883. DOI: 10.1063/1.1808504.

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